Epstein’s relationship to Prince Andrew was a very dangerous one. The reason; it gives a Controller influence over a very powerful man. A man who has the potential to become more powerful. At some point in his career the devil could call in the debt and a bad decision could be made with dire consequences. Imagine if Churchill had been friends of an Epstein like character and opted for a peace agreement with, rather than fight, the Third Reich.
The Prince has had some intriguing dealings with some shady characters. He is allegedly buddies with a Libyan arms smuggler, Tarak Kaituni. He has been criticized for his relationship with the President of Azerbijan Ilham Aliyev. Aliyev has been accused by Amnesty International of human rights abuses.
According to this Vanity Fair article (November of 2020) the Prince allegedly traveled to meet Muamar Gaddafi and discussed the release of the Lockerbie Bomber, Abdelbaset al-Megrahi, who was released the following year.
Any influence on his affairs attributable to his friendship with Epstein is purely speculation. But it is suspicious. At the least it limits the amount of legitimacy he will wield in future political endeavors.